±èÁ¤Èñ(Kim Jung-Hee) - Seoul National University College of Medicine Department of Internal Medicine
ÃÖ¼ºÈñ(Choi Sung-Hee) - Seoul National University College of Medicine Department of Internal Medicine
ÀÓ¼ö(Lim Soo) - Seoul National University College of Medicine Department of Internal Medicine
À±Áö¿ø(Yoon Ji-Won) - Seoul National University College of Medicine Department of Internal Medicine
°¼±¹Ì(Kang Seon-Mee) - Seoul National University Bundang Hospital Department of Internal Medicine
±è±â¿õ(Kim Ki-Woong) - Seoul National University Bundang Hospital Department of Neuropsychiatry
ÀÓÀ翵(Lim Jae-Young) - Seoul National University Bundang Hospital Department of Rehabilitation Medicine
(Cho Nam-H.) - Ajou University School of Medicine Department of Preventive Medicine
ÀåÇÐö(Jang Hak-Chul) - Seoul National University College of Medicine Department of Internal Medicine
Abstract
Age-related body composition changes such as sarcopenia and obesity affect functional decline in the elderly. We investigated the relationship between body composition parameters and functional limitation in older Korean adults. We enrolled 242 men and 231 women aged ¡Ã 65 yr from the Korean elderly cohort. We used appendicular skeletal muscle mass (ASM) divided by height2 (ASM/Ht2) and ASM divided by weight (ASM/Wt). The isokinetic strength of knee extensor muscles were measured using an isokinetic device. Functional limitations were assessed using the Short Physical Performance Battery (SPPB) score less than nine. Men within the bottom tertile of ASM/Ht2 confer an increased risk for functional limitation compared with those within the top tertile (OR, 6.24; 95% CI, 1.78-22.0). However, in women, subjects within the lowest ASM/Wt tertile had a higher risk compared with those within the highest tertile instead of ASM/Ht2 (OR, 7.60; 95% CI, 2.25-25.7). Leg muscle strength remained the strong measure even after controlling for muscle mass only in women. Only large waist circumference was positively associated with functional limitation only in women. We might consider a different muscle index to assess functional limitation according to the gender.
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Sarcopenia, Obesity, Functional Limitation
KMID :
0191120130280071041
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À¯È¿¼º°á°ú(Recomendation)
Men had significantly higher muscle mass and leg muscle strength than women, whereas fat mass and percentage fat mass were significantly greater in women. The percentage of subjects with functional limitation and arthritis was much higher in women than in men. Alcohol drinking, current smoking and hypertension were observed more in men compared to women. The prevalence of diabetes mellitus, stroke, and heart disease did not differ significantly between men and women.